The hymn All Creation Rejoices in Thee is part of the Divine Liturgy of St. Basil, and was written by St. John of Damascus. (He appears in this icon, to the left of the Theotokos, presenting his scroll to her.)
All Creation rejoices in thee, O full of grace: the angels in heaven and the race of men, O sanctified temple and spiritual paradise, the glory of virgins, of whom God was incarnate and became a child, our God before the ages. He made thy body into a throne, and thy womb more spacious than the heavens. All of creation rejoices in thee, O full of grace: Glory be to thee.
True to the hymn, this icon features the Theotokos in the center, surrounded by the angels and numerous saints.
On the edges of the icon, there are also scenes from Genesis. The ones on the left represent the six days of creation; those on the right represent the lives and the fall of Adam and Eve, ending with their expulsion from Paradise.